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pentobarbital will lower the level or influence of cinacalcet by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.pentobarbital will minimize the level or result of naloxegol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Use of naloxegol with potent CYP3A4 inducers is not advisedpentobarbital w